Pancreatic Islets

Our perifused pancreatic islet system can be used to determine whether potential antidiabetic agents alter insulin secretion from ß-cells in vitro. The islet assay established and validated by RenaSci can, therefore, be used as an invaluable tool in early screening for Type 2 diabetes drug discovery programmes.

Key features of the assay include:

  • Direct measurement of perifused pancreatic islet insulin secretion in vitro
  • Detailed mechanistic studies
  • Medium-throughput screening

 

Glucose-stimulated insulin secretion from
perifused pancreatic islets

Glucose-stimulated insulin secretion from perifused pancreatic islets

 

GLP-1 increases glucose-stimulated insulin
secretion from perifused pancreatic islets

GLP-1 increases glucose-stimulated insulin secretion from perifused pancreatic islets

Get in touch to learn more about RenaSci’s in vitro pancreatic islet assay.

 

Contact us

For more details or information on how we can support your project please complete the contact form.