Experimental model of diabetes is induced in rodents by administration of streptozotocin (STZ), a glucosamine–nitrosourea compound that damages pancreatic β cells, resulting in hyperglycaemia. RenaSci have developed mouse and rat models of STZ/HFD Model of Type 2 Diabetes where animals administered STZ are fed a high fat diet.
The STZ/HFD Model of Type 2 Diabetes model is characterised by:
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