Simultaneous Measurement of Energy Expenditure and Energy Input in Rats

RenaSci now offers the TSE PhenoMaster for use with rats. The indirect calorimetry system enables simultaneous and automated measurement of the effects of novel antiobesity drugs on energy expenditure and energy input.

Parameters which can be measured include:

 

  • Oxygen consumption (VO2)
  • Carbon dioxide production (VCO2)
  • Energy expenditure (derived from VO2and VCO2)
  • Respiratory exchange ratio (RER; which estimates relative substrate utilization,┬áie shifts in fat and carbohydrate utilization)
  • Food and water intake
  • Meal and drink patterns (ie frequency and size)
  • Physical activity (measured as beam breaks on the x, y and z axis)